This collection consists primarily of Keys' business records and correspondence from the 1920s and early 1930s. The bulk of the material relates to the Curtiss Aeroplane and Motor Company/Curtiss-Wright Corporation and related firms, as well as Transcontinental Air Transport. The material includes business (operating) correspondence and records relating to Keys' financial interests.

The collection is divided into three series. The first series consists of materials dated through Keys' withdrawal from his aviation interests in 1932, followed by a second series of materials post-dating 1932. The final series consists of a small number of legal-sized documents not marked by Keys or his secretary and not otherwise placeable in either of the first two series. Because of the small amount of legal-sized material in the collection, the bulk of the collection has been stored in letter-sized containers; all legal-size documents have been placed in legal-sized containers at the end of the collection (Boxes 29-31) and a cross-reference note entered in the appropriate place in basic folder list. Larger materials have been placed in a single oversized box (Box 32) with cross-references in the folder list as appropriate.